He is Full Professor of Neurology at UniSR, Director of the School of Specialization in Neurology and President of the Degree Course in Physiotherapy of the same university. He is also Director of the Neurology and Neurorehabilitation Operating Units, the Multiple Sclerosis Center, the Stroke Unit, the Neurophysiology Service and the Quantitative Neuroimaging Unit of the San Raffaele Hospital in Milan. He has focused his research on the use of magnetic resonance techniques to understand the mechanisms that lead to the accumulation of irreversible disabilities in patients suffering from various neurological diseases. He has held and holds important positions in numerous national and international scientific societies. His activity as speaker and moderator in national and international conferences was very intense. He is the author of over 1220 articles in indexed journals, editor of about ten volumes, reviewer and member of the editorial board of various scientific journals; he is Editor in Chief of the Journal of Neurology. He is a passionate reader of novels and philosophical essays.